In vivo neural regeneration via AAV-NeuroD1 gene delivery to astrocytes in neonatal hypoxic-ischemic brain injury.

Miri KimSeokmin OhSongyeon KimIl-Sun KimJoowon KimJungho HanJi Woong AhnSeungsoo ChungJae-Hyung JangJeong Eun ShinKook In Park

Published in: Inflammation and regeneration (2024)

This study demonstrates that NeuroD1-mediated in vivo direct neuronal reprogramming technology through AAV gene delivery can be a novel regenerative therapy for neonatal HIBI.

Keyphrases

brain injury
stem cells
subarachnoid hemorrhage
cerebral ischemia
gene therapy
mesenchymal stem cells
cell therapy
bone marrow