Impact of Heart Rate Reduction with Maximal Tolerable Dose of Bisoprolol on Left Ventricular Reverse Remodeling.
Suk-Won ChoiSeong Woo HanWan Joo ShimYoungkeun AhnYong Jin KimByung-Su YooKyung Kuk HwangHui Kyung JeonMi Seung ShinKyu-Hyung RyuPublished in: Journal of Korean medical science (2018)
High baseline HR (≥ 75 bpm) showed an association with LVRR and improvement of NT-proBNP and GAS in patients with HFrEF. This seems to be due to a large HR reduction after treatments with bisoprolol. Trial registry at www.ClinicalTrials.gov, NCT00749034.