Design, Synthesis, Antitumor Activity Evaluation, and Molecular Dynamics Simulation of Some 2-Aminopyrazine Derivatives.
Hangrui CuiRuifeng ZhangXin XiongZhiwen CuiZhijian MinJinglong LiuXunping LiZhenli Min
Published in: Current computer-aided drug design (2024)
A new compound having a 2-aminopyrazine substructure with potent inhibitory activities against the H1975 and MDA-MB-231 cancer cells was obtained, meriting further investigation as an antitumor drug.