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Deletion of the whole NF1 gene in a three-generation family with neurofibromatosis type 1.

Qin DuHongxi ChenHongyu Zhou
Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)
Our findings are the first to identify whole NF1 deletion in a three-generation family with autosomal dominant NF1 and broaden the understanding of the genetic spectrum of NF1-associated NF1.
Keyphrases
  • signaling pathway
  • lps induced
  • pi k akt
  • nuclear factor
  • oxidative stress
  • inflammatory response
  • genome wide
  • copy number
  • toll like receptor