The hypertrophic amygdala shape associated with anxiety in patients with primary dysmenorrhea during pain-free phase: insight from surface-based shape analysis.

Siyi YuWei WeiLiying LiuXiaoli GuoZhifu ShenJin TianFang ZengFanrong LiangJie Yang

Published in: Brain imaging and behavior (2022)

The results of the current study demonstrated that the localized amygdala shape hypertrophy was present in PDM patients even in the pain-free phase. In addition, the mediator role of the hypertrophic amygdala indicates the potential target of amygdala for anxiety treatment in PDM treatment in the pain-free phase.

Keyphrases

functional connectivity
chronic pain
pain management
resting state
neuropathic pain
prefrontal cortex
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
spinal cord injury
risk assessment
combination therapy
human health
replacement therapy
data analysis