Lower Incidence of HIV-1 Blips Observed During Integrase Inhibitor-Based Combination Antiretroviral Therapy.
Suzan DijkstraL Marije HofstraTania MudrikovaAnnemarie M J WensingPatrick G A OomenAndy I M HoepelmanBerend J van WelzenPublished in: Journal of acquired immune deficiency syndromes (1999) (2022)
INSTI-based regimens display a low number of blips. Although we found no correlation with virologic failure, the occurrence of blips led to an increased clinical burden. Further research is needed to elucidate the implications and underlying mechanisms of these findings.