Characterization of metabolic features and potential anti-osteoporosis mechanism of pinoresinol diglucoside using metabolite profiling and network pharmacology.

Xin-Pu TuSi-Xian WuMeng-Yin LiZi-Hao ChenCheng-Jun LiuYan-Jie RuanJian-Bin ZengWei ShiJian-Hang LiuFeng-Xiang Zhang

Published in: Rapid communications in mass spectrometry : RCM (2024)

This study was the first to demonstrate the metabolic characteristics of PDG in vivo and its potential anti-osteoporosis mechanism, providing the data for further pharmacological validation of PDG in the treatment of osteoporosis.

Keyphrases

postmenopausal women
bone mineral density
body composition
electronic health record
big data
risk assessment
artificial intelligence