IL13Rα2 Promotes Proliferation and Outgrowth of Breast Cancer Brain Metastases.
Ricaurte Alejandro Marquez-OrtizMaria Jose Contreras-ZarateVesna TesicKaren L F Alvarez-ErasoGina KwakZachary LittrellJames C CostelloVarsha SreekanthD Ryan OrmondSana D KaramPeter KabosDiana M CittellyPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Non-genomic phenotypic adaptations at metastatic sites are critical to BM progression and patients' prognosis. This study opens the road to use IL13Rα2 targeting as a therapeutic strategy for BM.