Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma.
Carl FisherGirgis ObaidCarolyn NiuWarren FoltzAlyssa GoldsteinTayyaba HasanLothar LilgePublished in: Journal of clinical medicine (2019)
As lapatinib is approved for other oncological indications, a realization of its potential combination with PDT and in fluorescence-guided resection could be readily tested clinically. Furthermore, as its use would only be in acute settings, long-term resistance should not pose an issue as compared to its use as monotherapy.
Keyphrases
- low dose
- positive breast cancer
- combination therapy
- liver failure
- metastatic breast cancer
- photodynamic therapy
- high dose
- respiratory failure
- rectal cancer
- prostate cancer
- open label
- single molecule
- drug induced
- radical prostatectomy
- minimally invasive
- intensive care unit
- hepatitis b virus
- energy transfer
- quantum dots
- study protocol
- double blind