Cigarette smoke modifies neutrophil chemotaxis, neutrophil extracellular trap formation and inflammatory response-related gene expression.

P C WhiteJosefine Hirschfeld Michael R Milward Paul Roy CooperH J WrightJ B MatthewsIain L C Chapple

Published in: Journal of periodontal research (2018)

These results suggest that CSE can alter ex vivo neutrophil activation by mechanisms independent of SCN- and nicotine, and SCN- may contribute to the perturbed innate immune responses observed in smokers.

Keyphrases

immune response
inflammatory response
gene expression
smoking cessation
toll like receptor
dna methylation
lipopolysaccharide induced
dendritic cells
lps induced