ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis.

Kunxiang GongYinger HuangYanqin ZhengWenbo HaoKun Shi

Published in: Journal of translational medicine (2024)

ZSWIM4 inhibition enhanced EOC cell chemosensitivity by ameliorating intracellular glycine metabolism reprogramming, thus providing a new potential therapeutic strategy for EOC.

Keyphrases

reactive oxygen species
single cell
cell therapy