Activity in Group-Housed Home Cages of Mice as a Novel Preclinical Biomarker in Oncology Studies.
Stéphane TerryCéline GommetAnne-Cécile KeranguevenMickaël LeguetVincent ThéveninMickaël BerthelotLaurent BegoudFanny WindenbergerPierre LaineePublished in: Cancers (2023)
technology enabled the home cage monitoring of mice and non-invasive detection of animal activity disturbances. It can easily be integrated into a multimodal monitoring approach to better capture the different effects of oncology drugs on anti-tumor efficacy, toxicity, and safety and improve translation to clinical studies.