Effects of Dexmedetomidine on Immunomodulation and Pain Control in Videolaparoscopic Cholecystectomies: A Randomized, Two-Arm, Double-Blinded, Placebo-Controlled Trial.

Gustavo Nascimento SilvaVirna Guedes BrandãoMarcelo Vaz PerezKai-Uwe LewandrowskiRossano Kepler Alvim Fiorelli

Published in: Journal of personalized medicine (2023)

Dexmedetomidine decreased interleukin-6 4-6 h after surgery, likely by providing a sympatholytic effect. It provides good perioperative analgesia without respiratory depression. Implementing dexmedetomidine during laparoscopic cholecystectomy has a good safety profile and may lower healthcare expenditure due to faster postoperative recovery.

Keyphrases

cardiac surgery
healthcare
patients undergoing
pain management
acute kidney injury
chronic pain
depressive symptoms
double blind
postoperative pain
sleep quality
spinal cord
neuropathic pain
quality improvement
physical activity
study protocol
social media
spinal cord injury