FAM210A regulates mitochondrial translation and maintains cardiac mitochondrial homeostasis.

Jiangbin WuKadiam C Venkata SubbaiahOmar HedayaSi ChenJoshua MungerWai Hong Wilson TangChen Yan Peng Yao

Published in: Cardiovascular research (2023)

These results suggest that FAM210A is a mitochondrial translation regulator to maintain mitochondrial homeostasis and normal cardiomyocyte contractile function. This study also offers a new therapeutic target for treating ischemic heart disease.

Keyphrases

oxidative stress
skeletal muscle
left ventricular
heart failure
atrial fibrillation
endothelial cells