Toxic and Nutritional Optic Neuropathies-An Updated Mini-Review.
Jacek BajAlicja FormaJoanna KobakMagdalena TyczyńskaIga DudekAmr MaaniGrzegorz TeresińskiGrzegorz BuszewiczJacek JanuszewskiJolanta FliegerPublished in: International journal of environmental research and public health (2022)
Optic neuropathies constitute a group of conditions with various etiologies and might be caused by different factors; we can distinguish the genetic and acquired causes of optic neuropathies. Even though the symptoms are not highly specific, this condition is primarily characterized by unilateral or bilateral vision loss with worsening color detection. The loss may be acute or gradual depending on the causation. In this article, we included a specification of toxic optic neuropathy (TON) mainly triggered by alcohol abuse and also the usage of other substances, including drugs or methanol, as well as intoxication by metals, organic solvents, or carbon dioxide. Nutritional deficiencies, vitamin absorption disorder, and anemia, which usually appear during excessive alcohol intake, and their effect on the etiology of the optic neuropathy have been likewise discussed.
Keyphrases
- carbon dioxide
- optical coherence tomography
- optic nerve
- liver failure
- weight gain
- alcohol consumption
- chronic kidney disease
- drug induced
- genome wide
- respiratory failure
- loop mediated isothermal amplification
- hepatitis b virus
- gene expression
- health risk
- risk assessment
- intensive care unit
- dna methylation
- real time pcr
- health risk assessment
- climate change
- mechanical ventilation