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Identifying the natural products in the treatment of atherosclerosis by increasing HDL-C level based on bioinformatics analysis, molecular docking, and in vitro experiment.

Yilin ChenFengwei ZhangJijia SunLei Zhang
Published in: Journal of translational medicine (2023)
Based on our research, Genistein may have the effects of regulating HDL-C and anti-atherosclerosis. Its mechanism of action may be related to the regulation of LIPC, CETP, and APOA1 to improve lipid metabolism.
Keyphrases
  • molecular docking
  • bioinformatics analysis
  • cardiovascular disease
  • molecular dynamics simulations
  • smoking cessation