Ultra-Deep Genomic Sequencing of HCV NS5A Resistance-Associated Substitutions in HCV/HIV Coinfected Patients.
Enass A Abdel-HameedSusan D RousterCeejay L BoyceXiang ZhangJacek BiesiadaMario MedvedovicKenneth E ShermanPublished in: Digestive diseases and sciences (2018)
While the clinical significance of this observation may be limited in highly drug adherent populations, some HCV/HIV coinfected persons may be at greater risk of viral resistance if suboptimal dosing occurs.
Keyphrases
- hepatitis c virus
- human immunodeficiency virus
- antiretroviral therapy
- hiv positive
- hiv infected
- end stage renal disease
- hiv testing
- hiv aids
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- sars cov
- emergency department
- copy number
- dna methylation
- genetic diversity
- zika virus
- patient reported
- genome wide
- high throughput sequencing