Development of a rat model for type 2 diabetes mellitus peri-implantitis: A preliminary study.

Qingqing HeZhixiang MuAnnie ShresthaChao WangSi WangHan TangYihan LiJinlin SongPing JiYuanding HuangTao Chen

Published in: Oral diseases (2021)

These results describe a novel rat model which stimulate T2DM-PI in vivo, characterized by overwhelming inflammatory response and bone resorption. This model has a potential to be used for investigation of initiation, progression and interventional therapy of T2DM-PI.

Keyphrases

inflammatory response
glycemic control
bone loss
type diabetes
lipopolysaccharide induced
bone mineral density
lps induced
toll like receptor
soft tissue
stem cells
cardiovascular disease
bone regeneration
weight loss
insulin resistance
mesenchymal stem cells
skeletal muscle
smoking cessation
chemotherapy induced