With great power comes great vulnerability.
Rodrigo Leite de OliveiraLiqin WangRené BernardsPublished in: Molecular & cellular oncology (2018)
The clinical responses to targeted drugs are often transient and do not always translate into meaningful overall survival due to the development of resistance. We discuss here that the greater power of drug resistant cells can be associated with significant newly-acquired vulnerabilities that can be exploited therapeutically.