CD71 + erythroid cells suppress T-cell effector functions and predict immunotherapy outcomes in patients with virus-associated solid tumors.

Najmeh BozorgmehrIsobel OkoyeSiavash MashhouriJulia LuPetya KolevaJohn WalkerShokrollah Elahi

Published in: Journal for immunotherapy of cancer (2023)

Our results demonstrate that anemia by the expansion of CECs may enhance cancer progression. Notably, measuring the frequency of CECs may serve as a valuable biomarker to predict immunotherapy outcomes.

Keyphrases

induced apoptosis
chronic kidney disease
papillary thyroid
regulatory t cells
squamous cell carcinoma
cell cycle arrest
young adults
cell proliferation