Effectiveness and safety of methotrexate monotherapy in patients with Crohn's disease refractory to anti-TNF-α: results from the ENEIDA registry.
Francisco Mesonero GismeroJesús Castro-PoceiroJose M BenítezBlau CampsMarisa IborraAlicia López-GarcíaPaola TorresMaría EsteveJoan ToscaFederico BertolettiPedro AlmelaXavier Calvet CalvoIsabel VeraLuis BujandaFernando GomollónCristina RodríguezBeatriz AntolínDavid BusquetsAlejandro HernándezMontserrat RiveroDavid Monfort I MiquelAndrés Castaño-GarcíaFrancisco Javier García-AlonsoEugeni DomènechAntonio López-Sanrománnull nullPublished in: Alimentary pharmacology & therapeutics (2021)
The benefits observed suggest methotrexate monotherapy could be a valid option in Crohn's disease patients with previous failure to anti-TNFα.