Recent studies have supported that intensive antihypertensive treatment lowers the rates of cardiovascular events compared to standard treatment in older patients with hypertension, and it may also reduce the risk of cognitive decline. Intensive blood pressure lowering strategies are associated with reduced risk of cardiovascular morbidity and mortality as well as all-cause mortality, without compromising quality of life or functional status, and are relatively well tolerated in this patient population. Evidence suggests that maintaining systolic blood pressure below 130 mm Hg can yield cardiovascular and cognitive benefits in older patients with hypertension, particularly among those at risk of myocardial infarction or stroke. However, clinicians should vigilantly monitor for adverse events and engage in shared decision-making when pursuing intensive blood pressure goals tailored to individual risks and benefits.
Keyphrases
- blood pressure
- hypertensive patients
- cognitive decline
- cardiovascular events
- heart rate
- physical activity
- coronary artery disease
- middle aged
- community dwelling
- mild cognitive impairment
- atrial fibrillation
- type diabetes
- palliative care
- public health
- case report
- adipose tissue
- skeletal muscle
- human health
- insulin resistance
- subarachnoid hemorrhage