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Association between baseline blood pressure and the incidence of lenvatinib-induced hypertension in patients with thyroid cancer.

Yuma ShibutaniKazuko TajiriShinya SuzukiTomohiro EnokidaAtsunobu SagaraSusumu OkanoTakao FujisawaFumiaki SatoTetsuro YumotoMotohiko SanoToshikatsu KawasakiMakoto Tahara
Published in: Cancer medicine (2023)
Lenvatinib-induced hypertension appears the day after administration, and higher baseline blood pressure is a significant risk factor for developing hypertension grade ≥3. In cases of increased blood pressure with lenvatinib, early initiation of antihypertensives may prevent treatment interruption due to hypertension and maintain the therapeutic intensity of lenvatinib.
Keyphrases
  • blood pressure
  • hypertensive patients
  • heart rate
  • high glucose
  • diabetic rats
  • blood glucose
  • drug induced
  • type diabetes
  • endothelial cells
  • weight loss
  • combination therapy
  • arterial hypertension