Potential mechanisms of non-suicidal self-injury (NSSI) in major depressive disorder: a systematic review.

Baichuan WuHuifeng ZhangJinghong ChenJiaye ChenZhifen LiuYuqi ChengTifei YuanDai-Hui Peng

Published in: General psychiatry (2023)

This systematic review indicates that patients with MDD and NSSI might have specific psychosocial factors, aberrant brain functions and neurochemical metabolisms, HPA axis dysfunctions, abnormal pain perceptions and epigenetic alterations.

Keyphrases

major depressive disorder
systematic review
bipolar disorder
meta analyses
chronic pain
dna methylation
healthcare
gene expression
depressive symptoms
primary care
pain management
mental health
neuropathic pain
white matter
resting state
cerebral ischemia
spinal cord