Effect of Switching the Histamine-1 Receptor Antagonist Clemastine to Cetirizine in Paclitaxel Premedication Regimens: The H1-Switch Study.
Ruben MalmbergLeni van DoornJuul M CoxAlaa DaloulHalima EttafahiEsther Oomen-de HoopMichiel ZietseMonique E M M BosBirgit C P KochRoelof W F van LeeuwenPublished in: JCO oncology practice (2024)
Premedication containing oral cetirizine is as safe as premedication containing intravenous clemastine in preventing paclitaxel-induced HSR grade ≥3. These findings could contribute to optimization of care for patients and improve efficiency and sustainability.