A Systematic Review on the Genetic Contribution to Tinnitus.

Patricia Perez-CarpenaJose-Antonio Lopez-EscamezÁlvaro Gallego-Martinez

Published in: Journal of the Association for Research in Otolaryngology : JARO (2024)

The genetic contribution to tinnitus is starting to be revealed and it shows population-specific effects in European and Asian populations. The common allelic variants associated with tinnitus that showed replication are associated with noise-induced tinnitus. Although severe tinnitus has been associated with rare variants with large effect, their role on hearing or hyperacusis has not been established.

Keyphrases

hearing loss
copy number
genome wide
diabetic rats
gene expression
dna methylation
high glucose
oxidative stress