Chlorogenic acid induces apoptosis and cell-cycle arrest in colorectal cancer cells.

Ali Ghorbani RanjbaryAli BagherzadehSeyed Sina SabbaghiArshida FaghihiDelaram Nassaj KarimiShahryar NajiMohsen Kardani

Published in: Molecular biology reports (2023)

Considering the cytotoxicity and cell cycle arrest and induction of apoptosis in the colon cancer cell line by CGA, it can be concluded that CGA is a suitable option for the treatment of colon cancer.

Keyphrases

cell cycle arrest
cell death
pi k akt
signaling pathway
cell proliferation
oxidative stress
endoplasmic reticulum stress