Chemical genetics of regeneration: Contrasting temporal effects of CoCl2 on axolotl tail regeneration.

Nour W Al Haj BaddarVarun B DwarakaLarissa V PonomarevaJon S ThorsonS Randal Voss

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2021)

Our study identifies a temporal window from tail amputation to re-epithelialization, within which injury activated cells are highly sensitive to CoCl2 perturbation of redox homeostasis.

Keyphrases

stem cells
induced apoptosis
cell cycle arrest
genome wide
cell death
lower limb
endoplasmic reticulum stress
signaling pathway
gene expression
peripheral artery disease
molecularly imprinted
single molecule