Impaired nephrogenesis in neonatal rats with oxygen-induced retinopathy.

Mayu NakagawaNaoto NishizakiAmane EndoTomonosuke SomeyaYuta SaitoAkira MizutaniTaichi HaraYayoi MuranoKoji SakurayaSatoshi HaraDaisuke UminoDaishi HiranoShuichiro FujinagaYoshiyuki OhtomoToshiaki Shimizu

Published in: Pediatrics international : official journal of the Japan Pediatric Society (2017)

Renal impairment was caused by exposure to a hyperoxic environment during nephrogenesis, and the pathology of the impaired nephrogenesis in this OIR model reflects the characteristics of ROP observed in preterm infants.

Keyphrases

preterm infants
low birth weight
high glucose
drug induced
oxidative stress