The entire world is suffering from a new type of viral disease, occurred by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The present article briefly discussed the genome sequencing and interaction of host cells with SARS-CoV-2. The influence of pre-existing diseases such as diabetes, heart disease and age of the patients on COVID-19 infection is reviewed. The possible treatments of SARS-CoV-2 including antiviral drugs, Chinese traditional treatment and plasma therapy are elaborately discussed. The proper vaccine for COVID-19 is not available till date. However, the trials of pre-existing antiviral vaccines such as, chloroquine/hydroxychloroquine, remdesivir, ritonavir and lopinavir and their consequences are briefly presented. Further, the importance of new materials and devices for the detection and treatment of COVID-19 has also been reviewed. The polymerase chain reaction (PCR)-based, and non-PCR based devices are used for the detection of COVID-19 infection. The non-PCR based devices provide rapid results as compared to PCR based devices.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- real time pcr
- coronavirus disease
- loop mediated isothermal amplification
- type diabetes
- end stage renal disease
- induced apoptosis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- adipose tissue
- oxidative stress
- prognostic factors
- cell cycle arrest
- skeletal muscle
- mesenchymal stem cells
- antiretroviral therapy
- cell death
- replacement therapy
- bone marrow
- quantum dots
- pi k akt
- cell therapy
- single cell
- plasmodium falciparum