SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis.

Meng YuJonathan C BeanHailan LiuYang HeYongjie YangXing CaiKaifan YuZhou PeiHesong LiuLonglong TuKristine M CondeMengjie WangYongxiang LiNa YinNan ZhangJunying HanNikolas A ScarcelliPingwen XuYanlin HeYong XuChunmei Wang

Published in: Cell & bioscience (2022)

These results revealed a sexually dimorphic role of SK3 in POMC neurons in both energy and glucose homeostasis independent of body weight control, which was associated with the sex difference of SK current in a subpopulation of POMC + ERα + neurons.

Keyphrases

body weight
spinal cord
blood glucose
single cell
spinal cord injury
metabolic syndrome
adipose tissue
estrogen receptor
breast cancer cells