Changes in brain activation in breast cancer patients depend on cognitive domain and treatment type.

Sanne MenningMichiel B de RuiterDick J VeltmanWillem BoogerdHester S A OldenburgLiesbeth RenemanMichiel B de Ruiter

Published in: PloS one (2017)

Parietal hyperactivation after systemic treatment in the context of stable levels of executive task performance is compatible with a compensatory processing account of hyperactivation or maintain adequate performance levels. This over-recruitment of brain regions depends on the probed cognitive domain and may represent a response to decreased neural integrity after systemic treatment. Overall these results suggest different neurobehavioral trajectories in breast cancer patients depending on treatment type.

Keyphrases

working memory
resting state
multiple sclerosis
functional connectivity
molecular dynamics simulations
replacement therapy
blood brain barrier
smoking cessation
cerebral ischemia