Establishment and characterization of patient-derived cancer models of malignant peripheral nerve sheath tumors.
Rieko OyamaFusako KitoMami TakahashiEmi HattoriRei NoguchiYoko TakaiMarimu SakumotoZhiwei QiaoShunichi TokiMasato SugawaraYoshikazu TanzawaEisuke KobayashiFumihiko NakataniShintaro IwataAkihiko YoshidaAkira KawaiTadashi KondoPublished in: Cancer cell international (2020)
The established cell lines exhibit various characteristics, including proliferation and invasion potential. In addition, they had different mutation profiles and response to the anti-cancer agents. These observations suggest that the established cell lines will be useful for future research on MPNSTs.