Role of obesity and hypertension in the incidence of atrial fibrillation, ischaemic heart disease and heart failure in patients with diabetes.
Lucia La SalaAntonio E PontiroliPublished in: Cardiovascular diabetology (2021)
In a cohort study performed using primary care databases in a General Practitioners Network, Groenewegen et al. report a clear association between diabetes and incidence of the major chronic progressive heart diseases, notably heart failure (Groenewegen et al. in Cardiovasc Diabetol 20:123, 2021). However, no mention is made of body mass index and hypertension in the methods or in the results. Obesity is linked to hypertension and hypertension is a major risk factor for all cardiovascular diseases, and prospective studies have shown that obesity and hypertension contribute significantly to atrial fibrillation in persons with diabetes. The data would be improved by assessing the role of obesity and of hypertension in the incidence of heart diseases in these patients. This would also lead to a better and personalized treatment of patients with diabetes, for instance through weight loss and intensification of treatment of hypertension, to modify the incidence of atrial fibrillation, ischaemic heart disease and heart failure.
Keyphrases
- heart failure
- blood pressure
- atrial fibrillation
- weight loss
- type diabetes
- insulin resistance
- metabolic syndrome
- primary care
- cardiovascular disease
- risk factors
- bariatric surgery
- weight gain
- left atrial
- catheter ablation
- high fat diet induced
- oral anticoagulants
- big data
- end stage renal disease
- newly diagnosed
- adipose tissue
- roux en y gastric bypass
- left atrial appendage
- glycemic control
- ejection fraction
- chronic kidney disease
- direct oral anticoagulants
- artificial intelligence
- mitral valve
- arterial hypertension
- percutaneous coronary intervention
- prognostic factors
- gastric bypass
- general practice
- case control