Use of Cidofovir for Safe Transplantation in a Toddler with Acute Liver Failure and Adenovirus Viremia.
Vikram J ChristianRaiya SarwarJoseph C ReschSarah LimArif SomaniCatherine M Larson-NathShane McAllisterBeth K ThielenOyedele AdeyiSrinath ChinnakotlaHeli BhattPublished in: Case reports in transplantation (2022)
Recent reports of pediatric hepatitis cases may be associated with adenoviral infection although the exact relationship is unclear. There is the possibility of the ongoing SARS-CoV-2 environment, or other immunologic modifying factors. All patients presenting with hepatitis or acute liver failure should be screened for adenovirus and reported to state health departments. Cidofovir may be used to decrease viral load prior to liver transplantation, to decrease risk of severe adenoviral infection.