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Effects of glucagon-like peptide-1 receptor agonists on cardiovascular and renal outcomes: A meta-analysis and meta-regression analysis.

Satoshi YoshijiHiroto MinaminoDaisuke TanakaShunsuke YamaneNorio HaradaNobuya Inagaki
Published in: Diabetes, obesity & metabolism (2022)
The reduction in HbA1c, but not body weight, is associated with cardiovascular and renal outcomes. The magnitude of HbA1c reduction can be a surrogate for the cardiovascular and renal benefits of treatment with GLP-1 RAs.
Keyphrases
  • body weight
  • type diabetes
  • metabolic syndrome
  • skeletal muscle
  • combination therapy
  • glycemic control
  • replacement therapy