The prevalence of clarithromycin-resistant Helicobacter pylori isolates: a systematic review and meta-analysis.
Mohammad SholehSaeed KhoshnoodTaher AzimiJasem MohamadiVahab Hassan KaviarMarzieh HashemianSomayeh KaramollahiNourkhoda SadeghifardHedayat HeidarizadehMohsen HeidaryMorteza SakiPublished in: PeerJ (2023)
Overall CLA resistance rate was 27.53%, worldwide. The difference in CLA resistance rate among the included studies can be due to several reasons such as differences in antibiotic prescription rates in various geographic areas, use of different breakpoints or inaccurate criteria in performed studies, and the emergence of multidrug-resistant (MDR) strains.