Augmented Pla2g4c/Ptgs2/Hpgds axis in bronchial smooth muscle tissues of experimental asthma.

Yoshihiko ChibaWataru SutoHiroyasu Sakai

Published in: PloS one (2018)

AA metabolism is shifted towards PGD2 production in BSM tissues of asthma. Increased PGD2 level in the airways might be a cause of the BSM hyperresponsiveness in asthma.

Keyphrases

smooth muscle
chronic obstructive pulmonary disease
lung function
allergic rhinitis
gene expression
cystic fibrosis
air pollution