Lack of the transcription factor Nfix causes tachycardia in mice sinus node and rats neonatal cardiomyocytes.
Sara LandiFederica GiannettiPatrizia BenzoniGiulia CampostriniGiuliana RossiChiara PiantoniGiorgia BertoliChiara BonfantiLuca CarnevaliAnnalisa BucchiMirko BaruscottiGiorgia CarecciaGraziella MessinaAndrea BarbutiPublished in: Acta physiologica (Oxford, England) (2023)
current. In conclusion, our data provide the first demonstration of a role of Nfix that, increasing the L-type calcium current, modulates heart rate.