Serum Transaminases And Older Adults: Distribution And Associations With All-Cause Mortality.
Daniel I Clayton-ChubbAmmar MajeedStuart K RobertsHans G SchneiderIsabella ComminsJessica FitzpatrickRobyn L WoodsJoanne RyanSultana Monira HussainNatassia TanJohn S LubelCammie TranAlexander D HodgeJohn J McNeillWilliam W KempPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)
Low ALT levels independently confer an increased hazard of mortality for older males and females; low AST only impacted older male survival. Further evaluation of mechanisms would be worthwhile, and re-evaluating the lower limit of normal for ALT in older adults should be considered.