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Nucleotide excision repair deficiency in melanoma in response to UVA.

Heather C MurrayVicki E MaltbyDoug W SmithNikola A Bowden
Published in: Experimental hematology & oncology (2016)
These findings support that NER activity is reduced in melanoma cells due to deficient GGR. Further investigation into the role of NER in UVA-induced melanomagenesis is warranted and may have implications for melanoma treatment.
Keyphrases
  • skin cancer
  • diabetic rats
  • replacement therapy
  • combination therapy
  • wild type