Palladium-Catalyzed C-H Diarylation of Ferrocenecarboxylic Acids with Aryl Iodides.

Palladium-catalyzed C-H diarylation of ferrocenes is described. In the presence of 10 mol % Pd(OAc)2, direct C-H diarylation reactions of commercially available ferrocenecarboxylic acid with aryl iodides proceeded smoothly to afford diarylated ferrocenes bearing a variety of functional groups in moderate to good yields. The carboxylic group could also act as a remote directing group to result in the third arylation on the other Cp ring of ferrocene.