Synthesized Anti-HER2 Trastuzumab-MCC-DM1 Conjugate: An Evaluation of Efficacy and Cytotoxicity.

Soodabeh Shafiee Roya MirzaeiMalihe SalehiNeda JaliliAmir TaheriLeila Farahmand

Published in: Iranian journal of immunology : IJI (2023)

Trastuzumab-MCC-DM1 was found effective against HER2+ tumors. The potency of this synthesized conjugate brings it closer to the commercially available T-DM1.

Keyphrases

epidermal growth factor receptor
glycemic control
cancer therapy
metastatic breast cancer
type diabetes
adipose tissue
tyrosine kinase
drug delivery
oxide nanoparticles
skeletal muscle
insulin resistance