Association between tenofovir plasma trough concentrations in the early stage of administration and discontinuation of up to five years tenofovir disoproxil fumarate due to renal function-related adverse events in Japanese HIV-1 infected patients.

Hiroki YaguraDai WatanabeTakao NakauchiHiroyuki KushidaKazuyuki HirotaYasuharu NishidaMunehiro YoshinoTomoko UehiraTakuma Shirasaka

Published in: Journal of pharmaceutical health care and sciences (2024)

The results suggested that the importance of measuring TFV concentrations to evaluate the risk of developing renal function-related adverse events during long-term TDF administration.

Keyphrases

hiv infected patients
antiretroviral therapy
early stage
radiation therapy
drug induced
neoadjuvant chemotherapy