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Aquaporin-4 IgG antibodies: predictors of positivity and their relationship with neuropsychiatric disorders and white matter lesions in Juvenile systemic lupus erythematosus.

Yasmeen ShaabanHala El-MarsafawyReham M El-FarahatySherine El-ZinyAhmed M El-Refaey
Published in: Pediatric rheumatology online journal (2023)
jSLE patients with higher severity scores, neurological disorders, or white matter lesions could develop antibodies against AQP4. We recommend more studies for systematic screening of AQP4-Ab positivity in jSLE patients to confirm its relationship with neurological disorders.
Keyphrases
  • white matter
  • systemic lupus erythematosus
  • end stage renal disease
  • multiple sclerosis
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • blood brain barrier
  • patient reported