Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis.

Semih Alperen BostanHatice Yemenoglu Oğuz KoseKerimali AkyildizTolga MercantepeSinan SaralLevent TumkayaAdnan Yilmaz

Published in: Journal of periodontal research (2024)

Melatonin can significantly prevent the limited destructive effects of stress on periodontal tissues by suppressing RANKL-related osteoclastogenesis and oxidative stress.

Keyphrases

oxidative stress
diabetic rats
high glucose
gene expression
bone loss
stress induced
dna damage
drug induced
heat stress
induced apoptosis
depressive symptoms
endothelial cells
signaling pathway
physical activity
sleep quality
endoplasmic reticulum stress