Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.

Taotao LuHuihong LiYangjie ZhouWei WeiLinlin DingZengtu ZhanWeilin LiuJing TaoXie Hua Xue

Published in: Journal of neuroinflammation (2022)

Taken together, our study indicated that 24A alleviated GCI/R injury by inhibiting neuroinflammation and apoptosis through the regulation of the PI3K/AKT pathway.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
oxidative stress
endoplasmic reticulum stress
acute myocardial infarction
traumatic brain injury
signaling pathway
cell death
brain injury
lipopolysaccharide induced
cell proliferation
coronary artery disease
left ventricular
percutaneous coronary intervention