Biodistribution of [11C]-Metformin and mRNA Expression of Placentae Metformin Transporters in the Pregnant Chinchilla.
Maria Dahl OvergaardChristina Søndergaard DuvaldMikkel Holm VendelboSteen Bønløkke PedersenSteen JakobsenAage Kristian Olsen AlstrupEmmeli MikkelsenPer Glud OvesenMichael PedersenPublished in: Contrast media & molecular imaging (2019)
Since metformin did not pass the placenta barrier in the pregnant chinchilla, as it is known to do in humans, we do not suggest the chinchilla as a future animal model of metformin in pregnancies.