Prevalence and mortality of cryptococcal disease in adults with advanced HIV in an urban tertiary hospital in Sierra Leone: a prospective study.
Sulaiman LakohHannah RickmanMomodu SesaySartie KennehRachael BurkeMamadu BaldehDarlinda F JibaYusuf S TejanSonia BoyleComfort KoromaGibrilla F DeenFenella BeynonPublished in: BMC infectious diseases (2020)
A substantial prevalence of cryptococcal antigenaemia and poor outcome of cryptococcal disease were demonstrated in our study. The high mortality suggests a need for the HIV programme to formulate and implement policies on screening and pre-emptive fluconazole therapy for all adults with advanced HIV in Sierra Leone, and advocate for affordable access to effective antifungal therapies.