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Marine-Derived Stichloroside C2 Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis through the Mitogen-Activated Protein Kinase Signalling Pathway in Triple-Negative Breast Cancer Cells.

Chuang CuiChen-Huan DingFang-Fang LiuJing-Rong LuShi-Yun ZhengHou-Wen LinWei-Kang ZhuFan YangHe Li
Published in: Journal of oncology (2022)
STC2 exerts anti-TNBC activity, inhibits epithelial-mesenchymal transition (EMT), and induces apoptosis by regulating the cell cycle, EMT-related proteins, and MAPK signalling pathway.
Keyphrases
  • epithelial mesenchymal transition
  • cell cycle
  • signaling pathway
  • transforming growth factor
  • breast cancer cells
  • cell proliferation
  • pi k akt
  • oxidative stress